Coupling of the nucleus and cytoplasm: role of the LINC complex
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منابع مشابه
Comparison of Nucleus and Cytoplasm Diameter of Buccal Mucosa Cells in Cigarette Smokers and Nonsmokers: A Cytomorphometric Study using Feulgen and Papanicolaou Stains
Introduction: A decrease in cell size and an increase in nuclear dimension due to changes in the amount of DNA could be an indicator of early detection of malignant changes. This study aimed to compare the nuclear and cytoplasmic diameters of buccal mucosa cells in cigarette smokers and nonsmokers in a cytomorphometric study using Feulgen and Papanicolaou stains. Material & Methods: In this cas...
متن کاملThe Molecular Basis of LINC Complex Formation
The nucleus is the hallmark of the eukaryotic cell. It contains most of the genetic material and it separates the processes of replication and transcription from that of translation. Communication between the nucleus and the cytoplasm occurs mostly through openings in the nuclear envelope composed of nuclear pore complexes. These massive assemblies allow for regulated transport of macromolecule...
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The differential diagnosis between pleomorphic adenoma, the most common salivary gland neoplasm, microscopically, and two other common salivary gland neoplasms, meaning adenoid cystic carcinoma and mucoepidermoid carcinoma, is difficut.The purpose of this study was to determine the differences between pleomorphic adenoma, adenoid cystic carcinoma and mucoepidermoid carcinoma regarding the stain...
متن کاملThe LINC and NPC relationship - it's complicated!
The genetic information of eukaryotic cells is enclosed within a double-layered nuclear envelope, which comprises an inner and outer nuclear membrane. Several transmembrane proteins locate to the nuclear envelope; however, only two integral protein complexes span the nuclear envelope and connect the inside of the nucleus to the cytoplasm. The nuclear pore complex (NPC) acts as a gateway for mol...
متن کاملKeeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function.
Providing a stable physical connection between the nucleus and the cytoskeleton is essential for a wide range of cellular functions and it could also participate in mechanosensing by transmitting intra- and extra-cellular mechanical stimuli via the cytoskeleton to the nucleus. Nesprins and SUN proteins, located at the nuclear envelope, form the LINC (linker of nucleoskeleton and cytoskeleton) c...
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تاریخ انتشار 2011